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Portrait of Sperm cell

Anatomy · Cells & tissues

Sperm cell

The male gamete

Reproductive system · male germ cell

The male reproductive cell: a streamlined, swimming cell about 50–60 micrometres long, made up of a head, a midpiece and a tail. The head is a small oval packed with 23 tightly coiled chromosomes and capped by the acrosome, a bag of enzymes that lets the sperm penetrate the egg's coat. The midpiece is packed with mitochondria that power the tail, a whiplike flagellum. Sperm are made in the seminiferous tubules of the testis and mature in the epididymis.

How to spot them

  • â–ļTadpole-like cell with an oval head, a short thick neck and midpiece, and a long thin tail
  • â–ļHead only about 5 micrometres long, mostly nucleus, with a cap-like acrosome over the front
  • â–ļMidpiece packed with spirally arranged mitochondria
  • â–ļTail is a flagellum with a 9+2 arrangement of microtubules
  • â–ļAlmost no cytoplasm — the smallest cell in the human body by volume

What to know

A tadpole-shaped cell with a cap of digestive enzymes on the head, a mitochondrial midpiece and a whiplike tail

Sperm cell — the acrosome, midpiece and flagellum.

The cell that carries either an X or a Y chromosome, deciding the sex of a child

Sperm cell — the father's chromosome determines the sex.

The cap on its head releases enzymes that help it burrow through the coat of the egg

Sperm cell — the acrosome reaction.

Between 100 and 300 million are made every day in coiled tubules, taking about ten weeks from start to finish

Sperm cell — spermatogenesis in the seminiferous tubules.

First seen through the microscope in 1677 by Antonie van Leeuwenhoek and his assistant Johan Ham, who called them 'animalcules' (1677)

Sperm cell — early microscopy of semen.

It matures and gains the power of movement while stored in a tightly coiled tube behind the testis

Sperm cell — the epididymis.

The smallest cell in the body by volume, whose counterpart is the largest

Sperm cell — the egg is the largest.

Key ideas

  • Once inside the female tract a sperm becomes capable of fertilising in a process called capacitation. At the egg it undergoes the acrosome reaction, releasing enzymes, and its membrane fuses with the egg's.
  • Only the head enters the egg. The tail and midpiece mitochondria are broken down, so mitochondrial DNA is inherited from the mother.

Quick-fire facts

  • â€ĒTotal length is about 50–60 micrometres; the head is only about 5 micrometres long
  • â€ĒIt carries 23 chromosomes — half the normal number — which combine with the egg's 23 to make 46
  • â€ĒAround 100–300 million are made daily (OpenStax); the process takes roughly 64–74 days
  • â€ĒSpeeds of a few millimetres a minute are typical for progressive swimming
  • â€ĒSperm can survive in the female reproductive tract for several days
  • â€ĒWHO reference values place a normal concentration at about 16 million or more per millilitre of semen (lower fifth percentile)
  • â€ĒFertilisation normally takes place in the ampulla of the uterine tube

Drill it — 8 cards

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Sources