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Portrait of Lens

Anatomy · Eye, ear & senses

Lens

The eye's adjustable internal focusing element

Eye · behind the iris

A clear, flexible, biconvex disc about a centimetre across that sits directly behind the iris and pupil and in front of the vitreous body. It is slung from the ciliary body by a ring of fine zonular fibres and enclosed in an elastic capsule; changing its curvature lets the eye focus on near and far objects, a process called accommodation.

How to spot them

  • ▸A transparent biconvex disc just behind the pupil, the back surface more curved than the front
  • ▸Suspended by zonular fibres (the suspensory ligament) from the ciliary body
  • ▸Wrapped in a capsule that is the thickest basement membrane in the body
  • ▸Has no blood vessels or nerves; grows throughout life; stiffens with age

What to know

Held by a ring of fine fibres from the ciliary body; when the ciliary muscle contracts the fibres slacken and the disc rounds up

The lens and accommodation, as explained by Helmholtz

Enclosed in an elastic bag that is the thickest basement membrane in the body

The lens capsule

Adds new fibre cells like the layers of an onion throughout life, packed with proteins called crystallins

The lens; the oldest fibres sit in the central nucleus

By the mid-forties it stiffens, so that print must be held at arm's length

Presbyopia, loss of accommodation in the lens

Fragments of Perspex from shattered fighter-plane canopies, found harmlessly in pilots' eyes, inspired Harold Ridley's 1949 operation at St Thomas' Hospital (1949)

The first intraocular lens implant, an artificial replacement for the natural lens after cataract removal

Sits in a shallow dimple at the front of the vitreous body, the hyaloid fossa, immediately behind the iris

The lens, whose position is a favourite anatomy question

Develops in the embryo from a thickening of surface ectoderm called a placode that pinches off into a vesicle

The lens, a classic example of embryonic induction (by the optic vesicle)

Key ideas

  • For near vision the ciliary muscle contracts, the ring it forms shrinks, the zonular fibres go slack and the elastic capsule moulds the lens into a rounder shape with more focusing power.
  • The lens is avascular and lives off the aqueous humour; its clarity depends on ordered crystallin proteins, and cataract is what happens when they clump.

Quick-fire facts

  • •About 9–10 mm across and 3.5–5 mm thick in the adult, growing thicker with age
  • •Provides roughly 15–20 of the eye's approximately 60 dioptres, and is the adjustable part of the system
  • •The ciliary muscle is supplied by the parasympathetic fibres of the oculomotor nerve; the lens itself has no nerve supply
  • •Anterior surface has a single layer of epithelial cells; there is no epithelium on the posterior surface
  • •Hermann von Helmholtz proposed in 1855 that the lens rounds up for near vision when tension on it is released
  • •The absence of the natural lens is called aphakia; a lens lying out of position is ectopia lentis, a feature of Marfan syndrome
  • •Sir Harold Ridley (1906–2001) implanted the first artificial lens on 29 November 1949
  • •Cataract, clouding of the lens, is the leading cause of blindness worldwide, and cataract surgery is one of the commonest operations in the NHS

Drill it — 7 cards

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Sources